Title: Pediatric Cardiology / Aortopathy
Tags: aortopathy peds-cardio high-yield surgery loeys-dietz marfan pregnancy treatment delivery exercise screening veds

Q: What is the surgical threshold for Marfan syndrome?
A: ≥5.0 cm (Class I); ≥4.5 cm with risk factors (Class IIa)

Q: What is the surgical threshold for Loeys-Dietz syndrome (TGFBR1/2)?
A: ≥4.2 cm

Q: What are risk factors for earlier aortic surgery?
A: Rapid growth >0.5 cm/year, family history of dissection, planned pregnancy, significant AR

Q: What is first-line medical therapy for Marfan syndrome?
A: Beta-blocker OR ARB (equally effective - both Class I)

Q: What is preferred medical therapy for Loeys-Dietz syndrome?
A: ARB (preferred over beta-blocker)

Q: What defines vascular Ehlers-Danlos syndrome aortic management?
A: Most fragile vessels - surgery ONLY for emergencies; avoid unnecessary interventions

Q: What screening is required for first-degree relatives of TAA/dissection?
A: Aortic imaging (Class I recommendation)

Q: What are exercise restrictions for aortopathy patients?
A: Avoid intense isometric exercise, burst activities, collision/contact sports

Q: What is the pre-pregnancy surgical threshold for Marfan?
A: >4.5 cm aortic root

Q: When is cesarean section indicated for aortopathy?
A: Aortic diameter ≥4.5 cm