COVID-19 / MIS-C Flashcards

Q: What is MIS-C? A: Multisystem Inflammatory Syndrome in Children - hyperinflammatory response 2-6 weeks after COVID Tags: misc, definition, high-yield

Q: What is the median age for MIS-C? A: 8 years Tags: misc, epidemiology

Q: What are the cardiac manifestations of MIS-C? A: Cardiomyopathy (28-55%), coronary aneurysms (12-21%), myocarditis (18%), pericardial effusion (23%) Tags: misc, cardiac, high-yield

Q: What are the CDC diagnostic criteria for MIS-C? A: Age <21, fever ≥24h, lab inflammation, severe illness, ≥2 organ involvement, COVID evidence, no alternative diagnosis Tags: misc, diagnosis

Q: What is the treatment for MIS-C? A: IVIG 2g/kg + methylprednisolone 1-2 mg/kg/day; anakinra for refractory cases Tags: misc, treatment, high-yield

Q: What is the cardiac follow-up schedule after MIS-C? A: Echo+ECG at 7-14 days, 4-6 weeks, 3-6 months; annual if residual abnormality Tags: misc, follow-up, high-yield

Q: What is exercise restriction after MIS-C with cardiac involvement? A: None: 2 weeks; Mild: 3 months; Moderate-severe: 6 months minimum Tags: misc, return-to-play

Q: What testing is required before return to sports after MIS-C? A: Normal echo, normal Holter (if arrhythmias), normal stress test, cardiology clearance Tags: misc, return-to-play