Pediatric Heart Transplant Flashcards

Q: What is the most common indication for pediatric heart transplant? A: Cardiomyopathy (DCM most common) - ~60% of transplants Tags: transplant, indications, high-yield

Q: What percentage of pediatric transplants are bridged with VAD? A: 36% (increased from 25% in 2010) Tags: transplant, vad, high-yield

Q: Is VAD or ECMO preferred for bridge-to-transplant? A: VAD - better outcomes, reduces waitlist mortality Tags: transplant, bridge, high-yield

Q: What is 1-year survival after pediatric heart transplant? A: ~90% Tags: transplant, outcomes

Q: What is 5-year survival after pediatric heart transplant? A: ~75% Tags: transplant, outcomes

Q: What is the leading cause of late graft failure? A: Cardiac allograft vasculopathy (CAV) Tags: transplant, cav, high-yield

Q: What medication is given to ALL transplant recipients regardless of lipids? A: Statins (for CAV prevention) Tags: transplant, statins, high-yield

Q: What vaccines must be completed BEFORE transplant? A: All age-appropriate vaccines (live vaccines contraindicated post-transplant) Tags: transplant, vaccines, high-yield

Q: What are the main immunosuppression maintenance drugs? A: Tacrolimus (CNI) + mycophenolate (antimetabolite) + steroids (tapered) Tags: transplant, immunosuppression

Q: What is the difference between ACR and AMR? A: ACR = T-cell mediated (treat with steroids); AMR = antibody mediated (treat with plasmapheresis, IVIG, rituximab) Tags: transplant, rejection