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Chest Pain in Children

Learning Objectives

Core Knowledge & Clinical Reasoning

  • [ ] Recognize that cardiac causes account for <5% of pediatric chest pain
  • [ ] Identify the common non-cardiac causes (musculoskeletal, GI, anxiety)
  • [ ] Apply red flag criteria to identify the rare cardiac causes requiring urgent evaluation
  • [ ] Formulate appropriate workup based on history and exam findings

Communication & Counseling

  • [ ] Reassure families when evaluation suggests benign etiology
  • [ ] Educate on when to seek re-evaluation

Key Concept

Cardiac causes account for <5% of pediatric chest pain Most chest pain in children is benign musculoskeletal or idiopathic

Quick Reference: Chest Pain Evaluation Algorithm

Etiology of Pediatric Chest Pain

Category Prevalence Examples
Musculoskeletal 30-40% Costochondritis, muscle strain, precordial catch
Idiopathic 20-40% No identifiable cause
Pulmonary 10-20% Asthma, pneumonia, pneumothorax
GI 5-10% GERD, esophagitis
Psychogenic 5-15% Anxiety, panic, hyperventilation
Cardiac <5% Pericarditis, arrhythmia, structural

Common Benign Causes

Precordial Catch Syndrome (Texidor's Twinge)

  • Age: Adolescents, young adults
  • Character: Sharp, sudden, well-localized to left chest
  • Duration: Seconds to minutes
  • Trigger: Often at rest, may worsen with breathing
  • Resolution: Resolves spontaneously
  • Management: Reassurance only

Costochondritis

  • Character: Sharp or aching anterior chest pain
  • Exam: Reproducible with palpation of costochondral junctions
  • Management: NSAIDs, reassurance

Musculoskeletal Strain

  • History: Often after exercise, lifting, new activity
  • Exam: Reproducible with movement or palpation
  • Management: Rest, NSAIDs

RED FLAGS: Cardiac Chest Pain

Red Flag Concern
Exertional chest pain Ischemia (AAOCA, HCM, AS)
Associated syncope Arrhythmia, structural
Palpitations with pain Arrhythmia
Family history of SCD <50y Inherited cardiac disease
Family history of cardiomyopathy HCM, ARVC
Known heart disease Disease-related
Fever + chest pain Pericarditis, myocarditis
Recent viral illness + new pain Myocarditis, pericarditis
Marfanoid habitus Aortic dissection
Abnormal exam (murmur, rub, abnormal pulses) Structural disease

Cardiac Causes to Know

Pericarditis

  • Sharp, pleuritic pain improved by leaning forward
  • Friction rub on exam
  • ECG: diffuse ST elevation, PR depression
  • Echo: effusion

Myocarditis

  • Often preceded by viral illness
  • May have heart failure symptoms
  • Troponin elevated
  • ECG changes variable

Arrhythmia

  • Palpitations prominent
  • Pain during episodes
  • ECG may capture rhythm

Structural (Rare)

  • AAOCA: Exertional pain, may have syncope
  • HCM: Exertional, family history
  • Severe AS: Exertional

Coronary (Very Rare in Children)

  • Kawasaki disease with CAA
  • Anomalous left coronary from PA (infants)

Clinical Approach

CHEST PAIN
    │
    ▼
HISTORY & EXAM
    │
    ├── RED FLAGS present?
    │        │
    │        YES → ECG + Cardiology referral
    │              Consider: Echo, Troponin, CXR
    │
    └── NO RED FLAGS
             │
             ├── Reproducible with palpation?
             │        │
             │        YES → Musculoskeletal
             │              Reassurance, NSAIDs
             │
             ├── Sharp, brief, at rest?
             │        │
             │        YES → Precordial catch
             │              Reassurance
             │
             ├── GI symptoms?
             │        │
             │        YES → Consider GERD
             │              Trial PPI
             │
             └── Anxiety features?
                      │
                      YES → Psychogenic
                            Address anxiety

When to Get an ECG

ECG INDICATED

  • Any red flag present
  • Exertional symptoms
  • Palpitations
  • Syncope or near-syncope
  • Family history of SCD or cardiomyopathy
  • Abnormal cardiac exam

ECG NOT ROUTINELY NEEDED

  • Classic musculoskeletal pain
  • Precordial catch syndrome
  • Clear non-cardiac etiology
  • Normal exam, no red flags

When to Refer to Cardiology

  • Exertional chest pain
  • Chest pain with syncope
  • Abnormal ECG
  • Elevated troponin
  • Pericardial friction rub
  • Significant murmur
  • Family history of SCD/cardiomyopathy
  • Known structural heart disease

Board Pearls

Pearl: Cardiac causes = <5% of pediatric chest pain

Most is musculoskeletal or idiopathic

Pearl: Exertional chest pain = RED FLAG

Requires cardiac evaluation (ECG, consider echo)

Pearl: Precordial catch = Sharp, brief, at rest, self-limited

Classic benign cause in adolescents

Pearl: Reproducible with palpation = Musculoskeletal

Reassurance and NSAIDs appropriate

Self-Assessment

Q1: A 14-year-old has sharp left chest pain that started suddenly while sitting in class. It lasts 30 seconds, worsens with deep breath, then resolves completely. Exam is normal. What is the most likely diagnosis?

Answer **Answer**: Precordial catch syndrome (Texidor's twinge) **Rationale**: Classic features - sudden onset at rest, sharp, brief, may worsen with breathing, completely resolves. No workup needed.

Q2: A 16-year-old athlete has chest pain during basketball practice. He has no syncope but feels his heart "racing." Family history reveals his uncle died suddenly at age 35. What is the most appropriate next step?

Answer **Answer**: ECG and cardiology referral **Rationale**: Multiple red flags - exertional chest pain, palpitations, family history of SCD. Must evaluate for HCM, AAOCA, channelopathy.

Key Guidelines

2021 AHA Scientific Statement: Chest Pain in Children and Adolescents Circulation. 2021;144:e231-e248 PMID: 34459213


References

  • Friedman KG, et al. Circulation. 2021;144:e231-e248
  • Saleeb SF, et al. Pediatrics. 2016;138(3):e20154000